Structure of PDB 7bv3 Chain B Binding Site BS01

Receptor Information
>7bv3 Chain B (length=439) Species: 190515 (Siraitia grosvenorii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVELVFVPGPGIGHLSTALQIADLLLRRDHRLSVTVLSIPLPSRIRFISL
PQRQAVFETQKQNVKEAVAKLSDSSILAGLVLDMFCVTMVDVAKQLGVPS
YVFFTSSAGYLSFTSHLQDLSDRHGKETQQLMRSDVEIAVPGFTNPVPGK
VIPGVYFNKNMAEWLHDCARRFRETNGILVNTFSELESQVMDSFSDATAA
SQFPAVYAVGPILSLNAASSESQSGDEILKWLDQQPPSSVVFLCFGSKGS
LNPDQAREIAHALERSGHRFVWSLRQPSPKGKFEKPIEYDNIEDVLPEGF
LDRTAEMGRVIGWAPQVEILGHPATGGFVSHCGWNSTLESLWYGVPIATW
PMYAEQHFNAFEMGVELGLAVGISSESSIEEGVIVSAEKIEEGIRKLMGG
GGGEVRKLVKAKSEESRKSVMEGGSSFTSLNRFIDEVMK
Ligand information
Ligand IDUDP
InChIInChI=1S/C9H14N2O12P2/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChIKeyXCCTYIAWTASOJW-XVFCMESISA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO[P@@](=O)(O)OP(=O)(O)O)O)O
CACTVS 3.370O[CH]1[CH](O)[CH](O[CH]1CO[P](O)(=O)O[P](O)(O)=O)N2C=CC(=O)NC2=O
CACTVS 3.370O[C@H]1[C@@H](O)[C@@H](O[C@@H]1CO[P](O)(=O)O[P](O)(O)=O)N2C=CC(=O)NC2=O
OpenEye OEToolkits 1.7.0C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)O)O)O
ACDLabs 12.01O=P(O)(O)OP(=O)(O)OCC2OC(N1C(=O)NC(=O)C=C1)C(O)C2O
FormulaC9 H14 N2 O12 P2
NameURIDINE-5'-DIPHOSPHATE
ChEMBLCHEMBL130266
DrugBankDB03435
ZINCZINC000004490939
PDB chain7bv3 Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7bv3 Near-perfect control of the regioselective glucosylation enabled by rational design of glycosyltransferases
Resolution1.85 Å
Binding residue
(original residue number in PDB)		C281 G283 S284 W350 A351 Q353 H368 G370 N372 S373 E376 Y390
Binding residue
(residue number reindexed from 1)		C244 G246 S247 W313 A314 Q316 H331 G333 N335 S336 E339 Y353
Annotation score4
Enzymatic activity
Enzyme Commision number 2.4.1.-
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008194 UDP-glycosyltransferase activity
GO:0016757 glycosyltransferase activity
GO:0035251 UDP-glucosyltransferase activity
Cellular Component
GO:0009507 chloroplast

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:7bv3, PDBe:7bv3, PDBj:7bv3
PDBsum7bv3
PubMed
UniProtA0A346A6C4

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