Structure of PDB 7brg Chain B Binding Site BS01
Receptor Information
>7brg Chain B (length=426) Species:
10116
(Rattus norvegicus) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
SDLTVAVVLPLTNTSYPWSWARVGPAVELALARVKARPDLLPGWTVRMVL
GSSENAAGVCSDTAAPLAAVDLKWEHSPAVFLGPGCVYSAAPVGRFTAHW
RVPLLTAGAPALGIGVKDEYALTTRTGPSHVKLGDFVTALHRRLGWEHQA
LVLYADRLGDDRPCFFIVEGLYMRVRERLNITVNHQEFVEGDPDHYPKLL
RAVRRKGRVIYICSSPDAFRNLMLLALNAGLTGEDYVFFHLDVFGQSLKS
AQGLVPQKPWERGDGQDRSARQAFQAAKIITYKEPDNPEYLEFLKQLKLL
ADKKFNFTVEDGLKNIIPASFHDGLLLYVQAVTETLAQGGTVTDGENITQ
RMWNRSFQGVTGYLKIDRNGDRDTDFSLWDMDPETGAFRVVLNYNGTSQE
LMAVSEHKLYWPLGYPPPDVPKCGFD
Ligand information
>7brg Chain L (length=25) Species:
10116
(Rattus norvegicus) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
RSSCFGGRIDRIGAQSGLGCNSFRY
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
7brg
Structural insight into hormone-recognition and transmembrane signaling by the atrial natriuretic peptide receptor
Resolution
2.45 Å
Binding residue
(original residue number in PDB)
Y88 A91 L158 D160 R162 F165 E169 Y172 H185 Q186 E187 H195 K198
Binding residue
(residue number reindexed from 1)
Y88 A91 L158 D160 R162 F165 E169 Y172 H185 Q186 E187 H195 K198
Enzymatic activity
Enzyme Commision number
4.6.1.2
: guanylate cyclase.
Gene Ontology
Cellular Component
GO:0016020
membrane
View graph for
Cellular Component
External links
PDB
RCSB:7brg
,
PDBe:7brg
,
PDBj:7brg
PDBsum
7brg
PubMed
UniProt
P18910
|ANPRA_RAT Atrial natriuretic peptide receptor 1 (Gene Name=Npr1)
[
Back to BioLiP
]