Structure of PDB 7bai Chain B Binding Site BS01
Receptor Information
>7bai Chain B (length=121) Species:
9606
(Homo sapiens) [
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DKENKKLLCRKCKALACYTADVRVIEECHYTVLGDAFKECFVSRPHPKPK
QFSSFEKRAKIFCARQNCSHDWGIHVKYKTFEIPVIKIESFVVEDIATGV
QTLYSKWKDFHFEKIPFDPAE
Ligand information
>7bai Chain C (length=12) [
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gacgcuagcguc
............
Receptor-Ligand Complex Structure
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PDB
7bai
A conserved isoleucine in the RNA sensor RIG-I controls immune tolerance to mitochondrial RNA
Resolution
3.4 Å
Binding residue
(original residue number in PDB)
K849 F853 S854
Binding residue
(residue number reindexed from 1)
K48 F52 S53
Enzymatic activity
Enzyme Commision number
3.6.4.13
: RNA helicase.
External links
PDB
RCSB:7bai
,
PDBe:7bai
,
PDBj:7bai
PDBsum
7bai
PubMed
UniProt
O95786
|RIGI_HUMAN Antiviral innate immune response receptor RIG-I (Gene Name=RIGI)
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