Structure of PDB 7aov Chain B Binding Site BS01

Receptor Information
>7aov Chain B (length=377) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLDKRCSLASWIKENIKKKECCFYVEDGREGICKCGYPKVQHCDEAIKPE
DYMGEQWDKHRHVRETPTDAFGDISFGGLGQKTGKYVRVSSDTSCENLYQ
LMTEQWKLRSPNLLISVTGGAKNFYIKTHLKDKFRRGLIKVAQTTGAWIL
TGGTHAGVMKHVGMAVRDGQIVVIGVAPWGVIHNRSTLIHPEGRFPAYYS
LDEQGQGRLSCLDINHTHFLLVDDGTQGHYGVEIELRARLEKLISKLSLG
NRESGVTIPVVCVVLDGGPGTLNTIYNSMLNHTPCVVLEGSGRLADVIAH
VASVPVSKVTMALINRLLKRFFMQEYKNFTELQIIEWTKKIQDILRMPHL
LTVFRIDEDKNYDVDVAILQALLKASR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7aov Chain B Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7aov The crystal structure of TRPM2 MHR1/2 domain reveals a conserved Zn 2+ -binding domain essential for structural integrity and channel activity.
Resolution2.00002 Å
Binding residue
(original residue number in PDB)		C53 C65 C67 H74
Binding residue
(residue number reindexed from 1)		C21 C33 C35 H42
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7aov, PDBe:7aov, PDBj:7aov
PDBsum7aov
PubMed35634784
UniProtA0A0R4IMY7|TRPM2_DANRE Transient receptor potential cation channel subfamily M member 2 (Gene Name=trpm2)

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