Structure of PDB 7aoh Chain B Binding Site BS01

Receptor Information
>7aoh Chain B (length=1134) Species: 502057 (Vaccinia virus GLV-1h68) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EMDQRLGYKFLVPDPKAGVFYRPLHFQYVSYSNFILHRLHEILTVKRPLL
SFKNNTERIMIEISNVKVTPPDYSPIIASIKGKSYDALATFTVNIFKEVM
TKEGISITKISSYEGKDSHLIKIPLLIGYGNKNPLDTAKYLVPNVIGGVF
INKQSVEKVGINLVEKITTWPKFRVVKPNSFTFSFSSVSPPNVLPTRYRH
YKISLDISQLEALNISSTKTFITVNIVLLSQYLSRVSLEFIRRSLSYDMP
PEVVYLVNAIIDSAKRITESITDFNIDTYINDLVEAEHIKQKSQLTINEF
KYEMLHNFLPHMNYTPDQLKGFYMISLLRKFLYCIFHTSRYPDRDSMVCH
RILTYGKYFETLAHDELENYIGNIRNDIMNNHKNRGTYAVNIHVLTTPGL
NHAFSSLLSGKFKKSDGSYRTHPHYSWMQNISIPRSVGFYPSVRKYHPSQ
YLYFCSSDVPERGPQVGLVSQLSVLSSITNILTSEYLDLEKKICEYIRSY
YKDDISYFETGFPITIENALVASLNPNMICDFVTDFRRRKRMGFFGNLEV
GITLVRDHMNEIRINIGAGRLVRPFLVVDNGELMMDVCPELESRLDDMTF
SDIQKEFPHVIEMVDIEQFTFSNVCESVQKFRMMSKDERKQYDLCDFPAE
FRDGYVASSLVGINHNSGPRAILGCAQAKQAISCLSSDIRNKIDNGIHLM
YPERPIVISKALETSKIAANCFGQHVTIALMSYKGINQEDGIIIKKQFIQ
RGGLDIVTAKKHQVEIPLENFNNKERDRSNAYSKLESNGLVRLNAFLESG
DAMARNISSISFDVSEKYTDMYKSRVERVQVELTDKVKVRVLTMKERRPI
LGDKFTTRTSQKGTVAYVADETELPYDENGITPDVIINSTSIFSRKTISM
LIEVILTAAYSAKPYNNKGENRPVCFPSSNETSIDTYMQFAKQCYEHSNP
KLSDEELSDKIFCEKILYDPETDKPYASKVFFGPIYYLRLRHLTQDKATV
RCRGKKTKLIRQANEGRKRGGGIKFGEMERDCLIAHGAANTITEVLKDSE
EDYQDVYVCENCGDIAAQIKGINTCLRCSKLNLSPLLTKIDTTHVSKVFL
TQMNARGVKVKLDFERRPPSFYKPLDKVDLKPSF
Ligand information
Receptor-Ligand Complex Structure
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PDB7aoh Structural basis of the complete poxvirus transcription initiation process.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		R478 Q481 Q696 K890 H1020 T1035 K1036
Binding residue
(residue number reindexed from 1)		R462 Q465 Q680 K862 H992 T1007 K1008
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0001054 RNA polymerase I activity
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006360 transcription by RNA polymerase I
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7aoh, PDBe:7aoh, PDBj:7aoh
PDBsum7aoh
PubMed34556871
UniProtQ49PH2

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