Structure of PDB 7afk Chain B Binding Site BS01

Receptor Information
>7afk Chain B (length=224) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEA
LAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLTN
WKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKD
MGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGN
DDAIRAVTLYLGAVAATVREGRSQ
Ligand information
>7afk Chain 1 (length=456) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccgcacaagcgguggagcaugugguuuaauucgaugcaacgcgaagaacc
uuaccuggucuugacauccacggaaguuuucagagaugagaaugugccuu
cgggaaccgugagacaggugcugcauggcugucgucagcucguguuguga
aauguuggguuaagucccgcaacgagcgcaacccuuauccuuuguugcca
gcgguccggccgggaacucaaaggagacugccagugauaaacuggaggaa
gguggggaugacgucaagucaucauggcccuuacgaccagggcuacacac
gugcuacaauggcgcauacaaagagaagcgaccucgcgagagcaagcgga
ccucauaaagugcgucguaguccggauuggagucugcaacucgacuccau
gaagucggaaucgcuaguaaucguggaucagaaugccacggugaauacgu
ucccgg
.<<.<<..<<<<...<<<<<<<<........<<........>>.......
...<<<<<<<......<<<<<<<..<<<<<<<....>>>>>>>...<<..
..>>..>>>>>.>>.<<..<<<..<<<<<<.<.....<<<<<<<<.....
.>>..<<<<......>>>>..>>>>>>.....<<<..<<<<<<....<..
.<<<.....>>>.>.....>>>>>>.....<<<<<.....>>>>>.....
....>>>.....>...>>>...>>>>>>.>>...>>>>>>>......>>>
>>>>>.....<<<<<<<.....<<<..<<...<<<....>>>...>>...
.>>>.....>>>>>>>...........<<<<<<<........>>>>>>>.
..........>>>>.....<<<<<<<.........>>>>>>>......>>
...>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7afk A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Resolution4.9 Å
Binding residue
(original residue number in PDB)
R74 R95 L97 G98 G99 T102 N103 K105 T106 K131 I171
Binding residue
(residue number reindexed from 1)
R71 R92 L94 G95 G96 T99 N100 K102 T103 K128 I168
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7afk, PDBe:7afk, PDBj:7afk
PDBsum7afk
PubMed34088665
UniProtP0A7V0|RS2_ECOLI Small ribosomal subunit protein uS2 (Gene Name=rpsB)

[Back to BioLiP]