Structure of PDB 7acd Chain B Binding Site BS01

Receptor Information
>7acd Chain B (length=236) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NDYCQHFVDTGHRPQNFIRDRELIRLKDELIAKSNTPPMYLQADIEAFDI
RELTPKFDVILLEPPLEEYYRKCWTWDDIMKLEIDEIAAPRSFIFLWCGS
GEGLDLGRVCLRKWGYRRCEDICWIKTNKNNPLDPKAVFQRTKEHCLMGI
KGTVDIDLIITEEPEIGNIEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRP
GWLTVGPTLTNSNYNAETYASYFSAPNSYLTGCTEE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7acd Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7acd METTL3 Inhibitors for Epitranscriptomic Modulation of Cellular Processes.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D157 H332 H336
Binding residue
(residue number reindexed from 1)		D28 H177 H181
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7acd, PDBe:7acd, PDBj:7acd
PDBsum7acd
PubMed34237194
UniProtQ9HCE5|MET14_HUMAN N6-adenosine-methyltransferase non-catalytic subunit (Gene Name=METTL14)

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