Structure of PDB 6z8t Chain B Binding Site BS01

Receptor Information
>6z8t Chain B (length=646) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APSVVTGVAQSSPLTIVTNPKEPRQPVPASDGADYLKTIPGFAVIRNGGS
NGDPVLRGMFGSRLNILTNGGMMLGACPNRMDAPTSYISPETYDKLTVIK
GPQTVLWGPGASAGTILFEREPERFGELGSRVNASLLAGSNGRFDKVLDA
AAGNRLGYLRFTGNHAQSDDYEDGAGNTVPSRWKKWNGDVAVGWTPDEDT
LIELTAGKGDGEARYAGRGMDGSQFKRESLGLRFVKSNVSDVLEKVEAQV
YYNYADAIMDNFRLRTPDPSSMMPMPMASQVDRRTLGGRLAATWRWDDFK
LVTGVDAMRNEHRARGSKYDMMTDYYTDADQFPWSKDAVFHNYGAFGELT
WFAAERDRLIGGLRLDRASVKDYRQTLKHAMANPTANDTRADTLPSGFVR
YEHDLADSPTTLYAGLGHAERFPDYWELFSPKRGPNGSVNAFDKIKPEKT
TQLDFGLQYNGDKLQAWASGYVGVVQDFILFSYRSTQATNVDARIMGGEL
GASYQLTGNWKTDASLAYAWGKNSSDDRALPQIPPLEARFGLTYEEGDWS
AGSLWRVVAPQNRIARDQGNVVGKDFDKSAGFGVFSLNGAYRVTRNVKLS
AGVDNLFDKDYTEHLNKAGDAGFGFSANETVPEPGRTFWTKVDFSF
Ligand information
Ligand IDAG
InChIInChI=1S/Ag/q+1
InChIKeyFOIXSVOLVBLSDH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Ag+]
FormulaAg
NameSILVER ION
ChEMBLCHEMBL1230866
DrugBankDB14521
ZINC
PDB chain6z8t Chain B Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6z8t Acquisition of ionic copper by the bacterial outer membrane protein OprC through a novel binding site.
Resolution2.86 Å
Binding residue
(original residue number in PDB)		M147 M325
Binding residue
(residue number reindexed from 1)		M81 M259
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0015344 siderophore uptake transmembrane transporter activity
GO:0046872 metal ion binding
Biological Process
GO:0033214 siderophore-dependent iron import into cell
GO:0044718 siderophore transmembrane transport
Cellular Component
GO:0009279 cell outer membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6z8t, PDBe:6z8t, PDBj:6z8t
PDBsum6z8t
PubMed34762655
UniProtG3XD89

[Back to BioLiP]