Structure of PDB 6z8q Chain B Binding Site BS01

Receptor Information
>6z8q Chain B (length=639) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APSVSSPLTIVTNPKEPRQPVPASDGADYLKTIPGFAVIRNGGSNGDPVL
RGMFGSRLNILTNGGMMLGACPNRMDAPTSYISPETYDKLTVIKGPQTVL
WGPGASAGTILFEREPERFGELGSRVNASLLAGSNGRFDKVLDAAAGNRL
GYLRFTGNHAQSDDYEDGAGNTVPSRWKKWNGDVAVGWTPDEDTLIELTA
GKGDGEARYAGRGMDGSQFKRESLGLRFVKSNVSDVLEKVEAQVYYNYAD
HIMDNFRLRTPDPSSMMPMPMASQVDRRTLGGRLAATWRWDDFKLVTGVD
AMRNEHRARGSKYDMMTDYYTDADQFPWSKDAVFHNYGAFGELTWFAAER
DRLIGGLRLDRASVKDYRQTLKSGHMGHAMANPTANDTRADTLPSGFVRY
EHDLADSPTTLYAGLGHAERFPDYWELFSPKRGPNSVNAFDKIKPEKTTQ
LDFGLQYNGDKLQAWASGYVGVVQDFILFSYRESSTQATNVDARIMGGEL
GASYQLTGNWKTDASLAYAWGKNSSDDRALPQIPPLEARFGLTYEEGDWS
AGSLWRVVAPQNRIARDQGNVVGKDFDKSAGFGVFSLNGAYRVTRNVKLS
AGVDNLFDKDYTEHLNKAGANETVPEPGRTFWTKVDFSF
Ligand information
Ligand IDAG
InChIInChI=1S/Ag/q+1
InChIKeyFOIXSVOLVBLSDH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Ag+]
FormulaAg
NameSILVER ION
ChEMBLCHEMBL1230866
DrugBankDB14521
ZINC
PDB chain6z8q Chain B Residue 801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6z8q Acquisition of ionic copper by the bacterial outer membrane protein OprC through a novel binding site.
Resolution2.71 Å
Binding residue
(original residue number in PDB)		C143 M147 H323 M325
Binding residue
(residue number reindexed from 1)		C71 M75 H251 M253
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0015344 siderophore uptake transmembrane transporter activity
GO:0046872 metal ion binding
Biological Process
GO:0033214 siderophore-dependent iron import into cell
GO:0044718 siderophore transmembrane transport
Cellular Component
GO:0009279 cell outer membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6z8q, PDBe:6z8q, PDBj:6z8q
PDBsum6z8q
PubMed34762655
UniProtG3XD89

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