Structure of PDB 6yle Chain B Binding Site BS01

Receptor Information
>6yle Chain B (length=415) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDEQVIFTTNTSGTIASVHSFEQINLRQCSTQSRNSCVQVGNKYLFIAQA
QKALINVYNLSGSFKRESVEQRLPLPEILKCLEVVENDGVQYDRIQGVNH
NLPDFNLPYLLLGSTESGKLYIWELNSGILLNVKPMAHYQSITKIKSILN
GKYIITSGNDSRVIIWQTVDLVSPKPLCILHDHTLPVTDFQVSSSQGKFL
SCTDTKLFTVSQDATIRCYDLSLIKTPVLLATFTTPYSIKSIVLDPADRA
CYIGTAEGCFSLNLFYKLKGNAIVNLLQSAGVNTVQKGRVFSLVQRNLYA
MGQLVCENVLNSNVSCLEISMDGTLLLIGDTEGKVSIAEIYSKQIIRTIQ
TLTVGEVTNLLTNPYRLKIPNLQRVIFDGKNKGHLHDIWYQIGEPEADFN
AYLEQVKTQESIFSH
Ligand information
>6yle Chain K (length=24) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RNPYLIPDYPQPFEHLKLFTRELK
Receptor-Ligand Complex Structure
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PDB6yle Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		M1 E3 R270 D355 E372 Y374
Binding residue
(residue number reindexed from 1)		M1 E3 R249 D322 E339 Y341
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0005515 protein binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006261 DNA-templated DNA replication
GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication
GO:0006364 rRNA processing
GO:0030174 regulation of DNA-templated DNA replication initiation
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005656 nuclear pre-replicative complex
GO:0120330 rixosome complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6yle, PDBe:6yle, PDBj:6yle
PDBsum6yle
PubMed32668200
UniProtP53877|IPI3_YEAST Pre-rRNA-processing protein IPI3 (Gene Name=IPI3)

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