Structure of PDB 6xxr Chain B Binding Site BS01
Receptor Information
>6xxr Chain B (length=108) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
QSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGRKI
QDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFASA
MMHALEVL
Ligand information
>6xxr Chain F (length=5) Species:
32630
(synthetic construct) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
PPPPT
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
6xxr
Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Resolution
1.48 Å
Binding residue
(original residue number in PDB)
Y16 W23 K69 N71 F77 Q79 R81 V86
Binding residue
(residue number reindexed from 1)
Y13 W20 K66 N68 F74 Q76 R78 V83
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6xxr
,
PDBe:6xxr
,
PDBj:6xxr
PDBsum
6xxr
PubMed
33184177
UniProt
Q8N8S7
|ENAH_HUMAN Protein enabled homolog (Gene Name=ENAH)
[
Back to BioLiP
]
