Structure of PDB 6xup Chain B Binding Site BS01

Receptor Information

>6xup Chain B (length=401) Species: 2234 (Archaeoglobus fulgidus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GLTYRIGNGASVPISNTGELIKGLRNYGPYEVPSLKYNQIALIHNNQFSS
LINQLKSQISSKIDEVWHIHNINISEFIYDSPHFDSIKSQVDNAIDTGVD
GIMLVLPEYNTPLYYKLKSYLINSIPSQFMRYDILSNRNLTFYVDNLLVQ
FVSKLGGKPWILNVDPEKGSDIIIGTGATRIDNVNLFCFAMVFKKDGTML
WNEISPIVTSSEYLTYLKSTIKKVVYGFKKSNPDWDVEKLTLHVSGKRPK
MKDGETKILKETVEELKKQEMVSRDVKYAILHLNETHPFWVMPYEGTKVK
LSSKRYLLTLLQMVTPIKPLSVEIVSDNWTSEEYYHNVHEILDEIYYLSK
MNWRGFRSRNLPVTVNYPKLVAGIIANVNRYGGYPINPEGNRSLQTNPWF
L

Ligand information

>6xup Chain P (length=6) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

atcgtg

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6xup Archaeoglobus fulgidus Argonaute protein with DNA oligoduplex 5'-pATCGTGGCCACGAT
Resolution	1.9 Å
Binding residue (original residue number in PDB)	Y118 N119 T120 Y123 K127 Q137 F138 M139 R140 I143 R147 Y152 N155 Q159 K163 W299 P342 R380 R385 L427
Binding residue (residue number reindexed from 1)	Y109 N110 T111 Y114 K118 Q128 F129 M130 R131 I134 R138 Y143 N146 Q150 K154 W290 P316 R354 R359 L401

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003723	RNA binding
GO:0046872	metal ion binding

View graph for
Molecular Function

External links

PDB	RCSB:6xup, PDBe:6xup, PDBj:6xup
PDBsum	6xup
PubMed
UniProt	O28951\|PIWI_ARCFU Piwi protein (Gene Name=AF_1318)

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