Structure of PDB 6xdk Chain B Binding Site BS01

Receptor Information

>6xdk Chain B (length=355) Species: 522373 (Stenotrophomonas maltophilia K279a)

RAFNFSAGPATLPESVLRQAQAEMLDWHGSGASIVEMSHRGAEFMSVAAE
AEADLRRLLDIPDDYAVLFLSGGATTQQALIPLNFAAPGQRADYVVSGHW
GKTAVKQAGVYVDVNIAASSEANGYRELPARADWQLSRDAAYVHITANET
IHGVEFRDVPDTGNVPLIADFSSSIASEPLDVRRYGVIYAGAQKNLGPVG
VAVMIIRRDLLERSGQPRADIFDYRSHVARNTPPTWNWYLAGLVFKWMLA
EGGVTEFAKRNAAKAALVYGAIDGSGGFYRNEVAYAARSRMNIPFFLPDA
ELDARFVAEAKAAGLLALKGHKVVGGIRASLYNAMPLAGAEALVAFMADF
QQRHG

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 6xdk Chain B Residue 401

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6xdk Crystal structure of Phosphoserine aminotransferase (SerC) from Stenotrophomonas maltophilia K279a
• Resolution: 1.6 Å
• Binding residue (original residue number in PDB): G111 V114 D115
• Binding residue (residue number reindexed from 1): G109 V112 D113
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 2.6.1.52: phosphoserine transaminase.

Gene Ontology

Molecular Function

• GO:0004648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity
• GO:0008483 transaminase activity
• GO:0030170 pyridoxal phosphate binding

Biological Process

• GO:0006563 L-serine metabolic process
• GO:0006564 L-serine biosynthetic process
• GO:0008615 pyridoxine biosynthetic process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:6xdk, PDBe:6xdk, PDBj:6xdk
• PDBsum: 6xdk
• UniProt: B2FKF0|SERC_STRMK Phosphoserine aminotransferase (Gene Name=serC)