Structure of PDB 6xav Chain B Binding Site BS01

Receptor Information

>6xav Chain B (length=407) Species: 83333 (Escherichia coli K-12)

MNLTELKNTPVSELITLGENMGLENLARMRKQDIIFAILKQHAKDIFGDG
VLEILGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPK
EGERYFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTE
DLTARVLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLM
VLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVE
HKKDVIILLDSITRLARAYNTVKVLTGGVDANALHRPKRFFGAARNVEEG
GSLTIIATALIDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDY
NRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLINKLAMTKTND
DFFEMMK

Ligand information

>6xav Chain T (length=29)

gggtattcgccgtgtacctctcctagccc

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6xav Pre-termination Transcription Complex: Structure and Function.
• Resolution: 7.7 Å
• Binding residue (original residue number in PDB): G107 E108 R109
• Binding residue (residue number reindexed from 1): G102 E103 R104

Enzymatic activity

• Enzyme Commision number: 3.6.4.-

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0003723 RNA binding
• GO:0004386 helicase activity
• GO:0005515 protein binding
• GO:0005524 ATP binding
• GO:0008186 ATP-dependent activity, acting on RNA
• GO:0016787 hydrolase activity
• GO:0016887 ATP hydrolysis activity
• GO:0042802 identical protein binding

Biological Process

• GO:0006353 DNA-templated transcription termination

Cellular Component

• GO:0005829 cytosol
• GO:0016020 membrane

External links

• PDB: RCSB:6xav, PDBe:6xav, PDBj:6xav
• PDBsum: 6xav
• PubMed: 33296676
• UniProt: P0AG30|RHO_ECOLI Transcription termination factor Rho (Gene Name=rho)