Structure of PDB 6x90 Chain B Binding Site BS01

Receptor Information
>6x90 Chain B (length=344) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKFVTASYNVGYPAYGAKFLNNDTLLVAGGGGEGNNGIPNKLTVLRVDPT
KDTEKEQFHILSEFALEDNDDSPTAIDASKGIILVGCNENSTKITQGKGN
KHLRKFKYDKVNDQLEFLTSVDFDASTNADDYTKLVYISREGTVAAIASS
KVPAIMRIIDPSDLTEKFEIETRGEVKDLHFSTDGKVVAYITGSSLEVIS
TVTGSCIARKTDFDKNWSLSKINFIADDTVLIAASLKKGKGIVLTKISIK
SGNTSVLRSKQVTNRFKGITSMDVDMKGELAVLASNDNSIALVKLKDLSM
SKIFKQAHSFAITEVTISPDSTYVASVSAANTIHIIKLPLNYAN
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain6x90 Chain B Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6x90 Structural basis for the initiation of COPII vesicle biogenesis.
Resolution2.26 Å
Binding residue
(original residue number in PDB)		G32 E33 G34 N36 I38 D68
Binding residue
(residue number reindexed from 1)		G32 E33 G34 N36 I38 D68
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005085 guanyl-nucleotide exchange factor activity

View graph for
Molecular Function
External links
PDB RCSB:6x90, PDBe:6x90, PDBj:6x90
PDBsum6x90
PubMed33831355
UniProtP11655|SEC12_YEAST Guanine nucleotide-exchange factor SEC12 (Gene Name=SEC12)

[Back to BioLiP]