Structure of PDB 6ww4 Chain B Binding Site BS01

Receptor Information
>6ww4 Chain B (length=56) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARTKQTIHPGVTCDGCQMFPINGSRFKCRNCDDFDFCETCFKTKKHNTRH
TFGRIN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6ww4 Chain B Residue 2801 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6ww4 Structural Insight into Binding of the ZZ Domain of HERC2 to Histone H3 and SUMO1.
Resolution2.252 Å
Binding residue
(original residue number in PDB)		C2708 C2711 C2732 C2735
Binding residue
(residue number reindexed from 1)		C13 C16 C37 C40
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.26: HECT-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:6ww4, PDBe:6ww4, PDBj:6ww4
PDBsum6ww4
PubMed32726574
UniProtO95714|HERC2_HUMAN E3 ubiquitin-protein ligase HERC2 (Gene Name=HERC2);
P68431|H31_HUMAN Histone H3.1 (Gene Name=H3C1)

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