Structure of PDB 6wmq Chain B Binding Site BS01

Receptor Information
>6wmq Chain B (length=197) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLS
QHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAG
DLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQE
TLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6wmq Structural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERB beta.
Resolution2.55 Å
Binding residue
(original residue number in PDB)		V413 V417 K421 Q434 V435 L438 K439 L572 K576
Binding residue
(residue number reindexed from 1)		V33 V37 K41 Q54 V55 L58 K59 L192 K196
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6wmq, PDBe:6wmq, PDBj:6wmq
PDBsum6wmq
PubMed33571111
UniProtQ14995|NR1D2_HUMAN Nuclear receptor subfamily 1 group D member 2 (Gene Name=NR1D2)

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