Structure of PDB 6w6h Chain B Binding Site BS01

Receptor Information
>6w6h Chain B (length=629) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QALQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVLSRRTKNNPVLIGEP
GVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGSMVAGSKYRGEFEER
LKAVLDDIKNSAGQIITFIDELHTIVGAGADAGNMIKPMLARGELRLVGA
TTLDEYRKHIEKDAALERRFQQVYVGEPSVEDTIGILRGLKDRYEVHHGV
RITDSALVAAATLSDRYITARFLPDKAIDLVDEAASRLRMEIDSRPVEID
EVERLVRRLEIEEMALSKEEDEASAERLAKLRSELADQKEKLAELTTRWQ
NEKNAIEIVRDLKKEEVGPDDIADVVSAWTGIPAGRLLEGETAKLLRMED
ELGKRVIGQKAAVTAVSDAVRRSRAGVSDPNRPTGAFMFLGPTGVGKTEL
AKALADFLFDDERAMVRIDMSEYGEKHTVARLIGAPPGYVGYEAGGQLTE
AVRRRPYTVVLFDEIEKAHPDVFDVLLQVLDEGRLTDGHGRTVDFRNTIL
ILTSNLGSGGSAEQVLAAVRATFKPEFINRLDDVLIFEGLNPEELVRIVD
IQLAQLGKRLAQRRLQLQVSLPAKRWLAQRGFDPVYGARPLRRLVQQAIG
DQLAKMLLAGQVHDGDTVPVNVSPDADSL
Ligand information
>6w6h Chain N (length=26) Species: 1773 (Mycobacterium tuberculosis) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AAAAAAAAAAAAAAAAAAAAAAAAAA
Receptor-Ligand Complex Structure
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PDB6w6h Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		K250 Y251 Y655 V656
Binding residue
(residue number reindexed from 1)		K92 Y93 Y439 V440
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0009408 response to heat
GO:0034605 cellular response to heat
GO:0042026 protein refolding
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6w6h, PDBe:6w6h, PDBj:6w6h
PDBsum6w6h
PubMed34038719
UniProtP9WPD1|CLPB_MYCTU Chaperone protein ClpB (Gene Name=clpB)

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