Structure of PDB 6w3j Chain B Binding Site BS01

Receptor Information
>6w3j Chain B (length=218) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TLRSITSPLVAHRLKPIRQKTKKAVVSILDSEEVCVELVKEYASQEYVKE
VLQISSDGNTITIYYPNFPLADRPPSPTDNISRYSFDNLPEKYWRKYQYA
SRFVQLVRSKSPKITYFTRYAKCILMENSPGADFEVWFYDGVKIHKTEDF
IQVIEKTGKSYTLKSESEVNSLKEEIKMYMDHANEGHRICLALESIISEE
ERKTRSAPFFPIIIGRKP
Ligand information
>6w3j Chain C (length=22) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
IDDEMFYDDHLEAYFEQLAIPG
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6w3j Structural and Functional Analyses of the FAM46C/Plk4 Complex.
Resolution4.385 Å
Binding residue
(original residue number in PDB)		K600 I602 R603 Q604 T606 K607 K608 K685 Y688 F692 K699 K711
Binding residue
(residue number reindexed from 1)		K15 I17 R18 Q19 T21 K22 K23 K96 Y99 F103 K110 K122
Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
External links
PDB RCSB:6w3j, PDBe:6w3j, PDBj:6w3j
PDBsum6w3j
PubMed32433990
UniProtO00444|PLK4_HUMAN Serine/threonine-protein kinase PLK4 (Gene Name=PLK4)

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