Structure of PDB 6uro Chain B Binding Site BS01

Receptor Information
>6uro Chain B (length=378) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TFDGKRMRKAVNRKTIDYNPSVIKYLENRIWQRDQRDMRAIQPDAGYYND
LVPPIGMLNNPMNAVTTKFVRTSTNKVKCPVFVVRWTPEGRRLVTGASSG
EFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQSN
MNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILR
GHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTV
MEVKLNLNGNWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHP
VHEGLFASGGSDGSLLFWHVGVEKEVGGMEMAHEGMIWSLAWHPLGHILC
SGSNDHTSKFWTRNRPGDKMRDRYNLNL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6uro Structural Insights into the Human Pre-mRNA 3'-End Processing Machinery.
Resolution3.6 Å
Binding residue
(original residue number in PDB)
F43 D44 G45 R47 M48 R49 R54 F153 I156
Binding residue
(residue number reindexed from 1)
F2 D3 G4 R6 M7 R8 R13 F112 I115
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0031124 mRNA 3'-end processing

View graph for
Biological Process
External links
PDB RCSB:6uro, PDBe:6uro, PDBj:6uro
PDBsum6uro
PubMed31810758
UniProtQ9C0J8|WDR33_HUMAN pre-mRNA 3' end processing protein WDR33 (Gene Name=WDR33)

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