Structure of PDB 6uio Chain B Binding Site BS01

Receptor Information
>6uio Chain B (length=110) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NYFGSINISNANVKQAVWFAMKEYNKESEDKYVFLVDKILHAKLQITDRM
EYQIDVQISRSNCKKPLNNTENCIPQKKPELEKKMSCSFLVGALPWNGEF
NLLSKECKDV
Ligand information
Ligand IDI2I
InChIInChI=1S/I2/c1-2
InChIKeyPNDPGZBMCMUPRI-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 12.01
CACTVS 3.385
OpenEye OEToolkits 1.7.6		II
FormulaI2
Namemolecular iodine
ChEMBLCHEMBL1201225
DrugBankDB05382
ZINC
PDB chain6uio Chain B Residue 203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6uio Maturation of the functional mouse CRES amyloid from globular form.
Resolution1.83 Å
Binding residue
(original residue number in PDB)		N42 N44
Binding residue
(residue number reindexed from 1)		N10 N12
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004869 cysteine-type endopeptidase inhibitor activity
Biological Process
GO:0010466 negative regulation of peptidase activity
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0009986 cell surface

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6uio, PDBe:6uio, PDBj:6uio
PDBsum6uio
PubMed32601205
UniProtP32766|CST8_MOUSE Cystatin-8 (Gene Name=Cst8)

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