Structure of PDB 6u6x Chain B Binding Site BS01
Receptor Information
>6u6x Chain B (length=383) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
MKVINDPIHGHIELHPLLVRIIDTPQFQRLRYIKQLGGGYYVFPGASHNR
FEHSLGVGYLAGCLVHALGEKQPELQISERDVLCVQIAGLCHDLGHGPFS
HMFDGRFIPLARPEVKWTHEQGSVMMFEHLINSNGIKPVMEQYGLIPEED
ICFIKEQIVGLWPYKGRPENKSFLYEIVSNKRNGIDVAKWDYFARDCHHL
GIQNNFDYKRFIKFARVICARDKEVGNLYDMFHTRNSLHRRAYQHKVGNI
IDTMITDAFLKADDYIEITGAGGKKYRISTAIDDMEAYTKLTDNIFLEIL
YSTDPKLKDAREILKQIEYRNLFKKIKREDYESLPKEVASAKPKVLEDFI
VDVINMLIRVYCKKVDRKSLYAARQYFVQWCAD
Ligand information
>6u6x Chain G (length=4) [
Search DNA sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
cgcc
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
6u6x
Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification.
Resolution
2.58 Å
Binding residue
(original residue number in PDB)
Y155 V156 R372 H376 R451
Binding residue
(residue number reindexed from 1)
Y41 V42 R241 H245 R320
Enzymatic activity
Enzyme Commision number
3.1.5.-
External links
PDB
RCSB:6u6x
,
PDBe:6u6x
,
PDBj:6u6x
PDBsum
6u6x
PubMed
33531504
UniProt
Q9Y3Z3
|SAMH1_HUMAN Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (Gene Name=SAMHD1)
[
Back to BioLiP
]
