Structure of PDB 6u4a Chain B Binding Site BS01
Receptor Information
>6u4a Chain B (length=124) Species:
9606
(Homo sapiens) [
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SEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDY
HKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIV
LMAQALEKIFLQKVAQMPQEEVEL
Ligand information
>6u4a Chain D (length=11) Species:
32630
(synthetic construct) [
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WWIIPKVKKGC
Receptor-Ligand Complex Structure
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PDB
6u4a
Cyclic peptides can engage a single binding pocket through highly divergent modes.
Resolution
1.88 Å
Binding residue
(original residue number in PDB)
F55 W57 V63 L68 N116 D120 D121 I122
Binding residue
(residue number reindexed from 1)
F32 W34 V40 L45 N93 D97 D98 I99
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6u4a
,
PDBe:6u4a
,
PDBj:6u4a
PDBsum
6u4a
PubMed
33046654
UniProt
Q15059
|BRD3_HUMAN Bromodomain-containing protein 3 (Gene Name=BRD3)
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