Structure of PDB 6u3b Chain B Binding Site BS01

Receptor Information
>6u3b Chain B (length=34) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNADEVTVGKFYATFLIQEYFRKFKKRKEQGLVG
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6u3b Chain B Residue 1701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6u3b Arrhythmia mutations in calmodulin can disrupt cooperativity of Ca2+binding and cause misfolding.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		S1608 D1611
Binding residue
(residue number reindexed from 1)		S1 D4
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6u3b, PDBe:6u3b, PDBj:6u3b
PDBsum6u3b
PubMed32012279
UniProtQ13936|CAC1C_HUMAN Voltage-dependent L-type calcium channel subunit alpha-1C (Gene Name=CACNA1C)

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