Structure of PDB 6txi Chain B Binding Site BS01

Receptor Information

>6txi Chain B (length=164) Species: 243274 (Thermotoga maritima MSB8)

MMVISEKVRKALNDQLNREIYSSYLYLSMATYFDAEGFKGFAHWMKKQAQ
EELTHAMKFYEYIYARGGRVELEAIEKPPSNWNGIKDAFEAALKHEEFVT
QSIYNILELASEEKDHATVSFLKWFVDEQVEEEDQVREILDLLEKANGQM
SVIFQLDRYLGQRE

Ligand information

• Ligand ID: FE
• InChI: InChI=1S/Fe/q+3
• InChIKey: VTLYFUHAOXGGBS-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: [Fe+3]
• Formula: Fe
• Name: FE (III) ION
• DrugBank: DB13949
• PDB chain: 6txi Chain B Residue 208

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6txi A single residue can modulate nanocage assembly in salt dependent ferritin.
• Resolution: 1.759 Å
• Binding residue (original residue number in PDB): E19 E52 H55
• Binding residue (residue number reindexed from 1): E19 E52 H55
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 1.16.3.2: bacterial non-heme ferritin.

Gene Ontology

Molecular Function

• GO:0004322 ferroxidase activity
• GO:0008198 ferrous iron binding
• GO:0008199 ferric iron binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006826 iron ion transport
• GO:0006879 intracellular iron ion homeostasis
• GO:0006880 intracellular sequestering of iron ion

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol

External links

• PDB: RCSB:6txi, PDBe:6txi, PDBj:6txi
• PDBsum: 6txi
• PubMed: 34195748
• UniProt: Q9X0L2