Structure of PDB 6ttk Chain B Binding Site BS01
Receptor Information
>6ttk Chain B (length=285) Species:
9606
(Homo sapiens) [
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ANEVLLVVGGFGSQQSPIDVVEKYDPKTQEWSFLPSITRKRRYVASVSLH
DRIYVIGGYDGRSRLSSVECLDYTGVWYSVAPMNVRRGLAGATTLGDMIY
VSGGFDGSRRHTSMERYDPNIDQWSMLGDMQTAREGAGLVVASGVIYCLG
GYDGLNILNSVEKYDPHTGHWTNVTPMATKRSGAGVALLNDHIYVVGGFD
GTAHLSSVEAYNIRTDSWTTVTSMTTPRCYVGATVLRGRLYAIAGYDGNS
LLSSIECYDPIIDSWEVVTSMGTQRCDAGVCVLRE
Ligand information
>6ttk Chain F (length=7) Species:
9606
(Homo sapiens) [
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GGPPGGP
Receptor-Ligand Complex Structure
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PDB
6ttk
Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12.
Resolution
2.383 Å
Binding residue
(original residue number in PDB)
F289 Y434 I439 F481 Y512
Binding residue
(residue number reindexed from 1)
F11 Y152 I157 F199 Y230
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6ttk
,
PDBe:6ttk
,
PDBj:6ttk
PDBsum
6ttk
PubMed
32574548
UniProt
Q53G59
|KLH12_HUMAN Kelch-like protein 12 (Gene Name=KLHL12)
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