Structure of PDB 6ts2 Chain B Binding Site BS01

Receptor Information
>6ts2 Chain B (length=1120) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPSINVALKAAFPSPPYLVELLETAASDNTTIYYSLLDRIAKGHFAEATT
DKALYEKFLEVLRDDGHMDPEALSAFKLALSLRTATPRVEAHYQYYTATV
EPSLSGTQEGCDQWFLIDGEQYCSPTLDTSHGKVKGEDQLRTLPFDRKFG
VGSRDVILYADITSKSFAPFHEVAMDLAKKGKASYRVRYRRSPSHSRESL
SVNGYGVELVLKRTDYIVIADIKPLEKSELAALGMKAASFVMQSEKPFEA
LLKLTQDFPKYSNSLGSQNVSAEFEAEHRGNREVFLPEGSNVLWLNGLHL
IDRQIQPFGLVDLLTRERKLIKSVLDLGLTGQQAVDLLGHAEVAHAKSRN
TLIFPEDKNELTVLNVNKIYIENHDLMSKVPVIEASKESTRDDWAALTVV
ADLDDIEGQELVYYALRFRKSNDGVRLDIVHNPKDTSRSPSVLAQRLKSR
EDKLLDFTRFLDLETALETGEFEPDVAYDASLANFLASSNMKAGDNFVIL
NGRVLGPITSADDFKKEDFEVFLQAERRTRILPVYKALEDLGLDDKVSGP
LSAAKLTSVTALSTISDLPQGIFDNAPTVRTTLFKQWNSTYTSFEVGDAS
TATIFFVAVINPASEIGQRWVAVLKVLSELEGVHLRVFLNPTVMIEELPV
KRFYRYVLSSSPSFDESGKVKALSARFTGVPRETLLVVGMDVPPAWLVTS
KVAVDDLDNLRIKDIKAKRGTEHVEAIYELEHILIEGHSREIPGAHAPRG
VQLVLETENNPHFADTIIMANLGYFQFKANPGVYNIRLKEGRSSEIFTLE
SVGAKGWGPIPGDDNTEVVLMDFQGTTLYPRLRRKPGMEEEDVLEPSTHA
EINIFSVASGHLYERMLNIMMASVMHHTNHTVKFWFIEQFLSPSFKDFIP
HMAAEYGFKYEMVTYKWPHWLRQQKEKQREIWGYKILFLDVLFPLSLDKV
IFVDADQIVRTDMYDLVEHPLDGAPYGFAPMCDSRVEMEGYRFWKTGYWA
NYLKGKPYHISALYVVDLQRFRELAAGDRLRQQYHALSADPNSLANLDQD
LPNHMQFTIPIATLPQEWLWCETWCSDETLKDARTIDLCNNPKLDRARRQ
VPEWTKYDEEIAELARRVRE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6ts2 Chain B Residue 1604 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6ts2 Clamping, bending, and twisting inter-domain motions in the misfold-recognizing portion of UDP-glucose: Glycoprotein glucosyltransferase.
Resolution5.74 Å
Binding residue
(original residue number in PDB)		D1302 D1304 D1435
Binding residue
(residue number reindexed from 1)		D954 D956 D1087
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity
Biological Process
GO:0006486 protein glycosylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6ts2, PDBe:6ts2, PDBj:6ts2
PDBsum6ts2
PubMed33352114
UniProtG0SB58

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