Structure of PDB 6t2a Chain B Binding Site BS01

Receptor Information
>6t2a Chain B (length=197) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LTYSQTMELKDSMLQLDPNAKTWIDIEGRPEDPVEIAIYQPNNGQYIHFY
REPTDIKQFKQDSKHSHGIDIQDLFSVQPGLTSAVIESLPKNMVLSCQGA
DDIRKLLDSQNRRDIKLIDVSMQKDDARKFEDKIWDEYKHLCRMHTGIVT
QEVTPHCALLDCLMFEAAVIGSPQIPTPRPVLSRDLVFRTGPPRVVL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6t2a Chain B Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6t2a Inhibition of Arenaviridae nucleoprotein exonuclease by bisphosphonate
Resolution2.0 Å
Binding residue
(original residue number in PDB)		E400 C507 H510 C530
Binding residue
(residue number reindexed from 1)		E35 C142 H145 C157
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.13.-
External links
PDB RCSB:6t2a, PDBe:6t2a, PDBj:6t2a
PDBsum6t2a
PubMed
UniProtP19239|NCAP_MOPEI Nucleoprotein (Gene Name=N)

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