Structure of PDB 6szw Chain B Binding Site BS01

Receptor Information
>6szw Chain B (length=174) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MHTDGDKAFVDFLSDEIKEERKIQKHKTLPKMSGGWELELNGTEAKLVRK
VAGEKITVTFNINNSITSTPNFVVEVIKNDDGKKALVLDCHYPDIFSIRE
VSFQSTGESEWKDTNYTLNTDSLDWALYDHLMDFLADRGVDNTFADELVE
LSTALEHQEYITFLEDLKSFVKSQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6szw Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6szw Factor XII and kininogen asymmetric assembly with gC1qR/C1QBP/P32 is governed by allostery.
Resolution3.14 Å
Binding residue
(original residue number in PDB)		D185 H187
Binding residue
(residue number reindexed from 1)		D89 H91
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005759 mitochondrial matrix

View graph for
Cellular Component
External links
PDB RCSB:6szw, PDBe:6szw, PDBj:6szw
PDBsum6szw
PubMed32559765
UniProtQ07021|C1QBP_HUMAN Complement component 1 Q subcomponent-binding protein, mitochondrial (Gene Name=C1QBP)

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