Structure of PDB 6szi Chain B Binding Site BS01

Receptor Information
>6szi Chain B (length=1185) Species: 1245 (Leuconostoc mesenteroides) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSYVADSSGQTYYFDGNGQPLIGLQTIDGNLQYFNQQGVQIKGGFQDVNN
KRIYFAPNTGNAVANTEIINGKLQGRDANGNQVKNAFSKDVAGNTFYFDA
NGVMLTGLQTISGKTYYLDEQGHLRKNYAGTFNNQFMYFDADTGAGKTAI
EYQFDQGLVSQSNENTPHNAAKSYDKSSFENVDGYLTADTWYRPTDILKN
GDTWTASTETDMRPLLMTWWPDKQTQANYLNFMSSKGLGITTTYTAATSQ
KTLNDAAFVIQTAIEQQISLKKSTEWLRDAIDSFVKTQANWNKQTEDEAF
DGLQWLQGGFLAYQDDSHRTPNTDSGNNRKLGRQPINIDGSKDTTDGKGS
EFLLANDIDNSNPIVQAEQLNWLHYLMNFGSITGNNDNANFDGIRVDAVD
NVDADLLKIAGDYFKALYGTDKSDANANKHLSILEDWNGKDPQYVNQQGN
AQLTMDYTVTSQFGNSLTHGANNRSNMWYFLDTGYYLNGDLNKKIVDKNR
PNSGTLVNRIANSGDTKVIPNYSFVRAHDYDAQDPIRKAMIDHGIIKNMQ
DTFTFDQLAQGMEFYYKDQENPSGFKKYNDYNLPSAYAMLLTNKDTVPRV
YYGDMYLEGGQYMEKGTIYNPVISALLKARIKYVSGGQTMATDSSGKDLK
DGETDLLTSVRFGKGIMTSDQTTTQDNSQDYKNQGIGVIVGNNPDLKLNN
DKTITLHMGKAHKNQLYRALVLSNDSGIDVYDSDDKAPTLRTNDNGDLIF
HKTNTFVKQDGTIINYEMKGSLNALISGYLGVWVPVGASDSQDARTVATE
SSSSNDGSVFHSNAALDSNVIYEGFSNFQAMPTSPEQSTNVVIATKANLF
KELGITSFELAPQYRSSGDTNYGGMSFLDSFLNNGYAFTDRYDLGFNKAD
GNPNPTKYGTDQDLRNAIEALHKNGMQAIADWVPDQIYALPGKEVVTATR
VDERGNQLKDTDFVNLLYVANTKSSGVDYQAKYGGEFLDKLREEYPSLFK
QNQVSTGQPIDASTKIKQWSAKYMNGTNILHRGAYYVLKDWATNQYFNIA
KTNEVFLPLQLQNKDAQTGFISDASGVKYYSISGYQAKDTFIEDGNGNWY
YFDKDGYMVRSQQGENPIRTVETSVNTRNGNYYFMPNGVELRKGFGTDNS
GNVYYFDDQGKMVRDKYINDDANNFYHLNVDGTMS
Ligand information
Ligand IDGLC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL423707
DrugBank
ZINCZINC000003861213
PDB chain6szi Chain E Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6szi A specific oligosaccharide-binding site in the alternansucrase catalytic domain mediates alternan elongation.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		Q700 N703 S713 Y717
Binding residue
(residue number reindexed from 1)		Q462 N465 S475 Y479
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.1.5: dextransucrase.
Gene Ontology
Molecular Function
GO:0046527 glucosyltransferase activity
Biological Process
GO:0009250 glucan biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6szi, PDBe:6szi, PDBj:6szi
PDBsum6szi
PubMed32409580
UniProtQ9RE05

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