Structure of PDB 6sul Chain B Binding Site BS01

Receptor Information
>6sul Chain B (length=334) Species: 1408 (Bacillus pumilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MHKDVKAIYEESKILDEATHLYGVQRSDIHFIADAENYVYELKKDGESFI
LKITHTIRRSPDYILGEMEWLHHLAKGGLSVAKPIASLNGRDIEQVDDGQ
GGSFLLRVYEKAPGHKVEEADWNDELFYALGQYTGRMHKLTKSYQLSDPR
YKRQEWDEEEQLKLRKYVPADQTLVFEQADRLMEKLAKLPKNQDTYGLVH
ADLHHGNFHWDQGKITTFDFDDIGYNWFMNDISILLYNVLWYPVIPYEDK
AAFAGNFMKQFLKGYREENELGDEWLAYIPDFLRLRHVLIYGLLHQAFDL
ATIGDEEKAMLASFRSDIEQAAPITTFDFTKLSQ
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6sul Chain B Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6sul A kinase bioscavenger provides antibiotic resistance by extremely tight substrate binding.
Resolution1.35 Å
Binding residue
(original residue number in PDB)		N207 D219
Binding residue
(residue number reindexed from 1)		N207 D219
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.1.230: amicoumacin kinase.
Gene Ontology
Molecular Function
GO:0004413 homoserine kinase activity
GO:0005524 ATP binding
GO:0046872 metal ion binding
Biological Process
GO:0009088 threonine biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6sul, PDBe:6sul, PDBj:6sul
PDBsum6sul
PubMed32637600
UniProtA8FAR5

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