Structure of PDB 6scy Chain B Binding Site BS01

Receptor Information
>6scy Chain B (length=298) Species: 267377 (Methanococcus maripaludis S2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MITMKCRKCGKPSIYHQKHSGNNYCKECFIKETKRKVRKTLGRDVLKNNI
KVAMGLSGGKDSLVMAYLLNEYYKQIPNSNLIAIMVNEGIEGYRTDGIDA
AVKFCEEYGIEYKIVHFKDYLGTNLDEIVTMNPCSFCGVIRRKILNRVSI
EEKCDFLAIGHNLDDVAQAVMMNYIEGDVKKLAFLGKSLKHPKFVKRIKP
LEKIPEDEVLLLAEMLELKYHKSPCPYSCLSFRSEVSDITDNLEKNHPGS
KYSIVRGYERLLEHIEGECKICGGLSATEVCKVCSYGKNLGILEKSKF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6scy Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6scy The thiolation of uridine 34 in tRNA, which controls protein translation, depends on a [4Fe-4S] cluster in the archaeum Methanococcus maripaludis.
Resolution2.81 Å
Binding residue
(original residue number in PDB)		C6 C9 C28
Binding residue
(residue number reindexed from 1)		C6 C9 C28
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0005524 ATP binding
GO:0016740 transferase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0002098 tRNA wobble uridine modification
GO:0002143 tRNA wobble position uridine thiolation
GO:0008033 tRNA processing
GO:0034227 tRNA thio-modification
Cellular Component
GO:0002144 cytosolic tRNA wobble base thiouridylase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6scy, PDBe:6scy, PDBj:6scy
PDBsum6scy
PubMed37005440
UniProtQ6LXJ4

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