Structure of PDB 6s3n Chain B Binding Site BS01

Receptor Information
>6s3n Chain B (length=436) Species: 56957 (Thermus oshimai) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLSSEQQRAFLAVTQTPHPAHLITGPAGTGKTTLLYALQEFYKGRAVTLA
PTGTAALQARGQTVHSFFRFPARLLRYRHPEDIRPPGPHSPLRKAIEQME
VLILDEVGMVRVDLLEAMDWALRKTRKRLEEPFGGVKVLLLGDTRQLEPV
VPGGEEALYIARTWGGPFFFQAHVWEEVALRVHRLWESQRQREDPLFAEL
LKRLRQGDPQALETLNRAAVRPDGGEEPGTLILTPRRKEADALNLKRLEA
LPGKPLEYQAQVKGEFAETDFPTEAALTLKKGAQVILLRNDPLGEYFNGD
LGWVEDLEAEALAVRLKRNGRRVVIRPFVWEKIVYTYDSEREEIKPQVVG
TFRQVPVRLAWALTVHKAQGLTLDKVHLELGRGLFAHGQLYVALTRVRRL
QDLSLSRPIAPTELLWRPEVEVFETRIQEGIWQKSH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6s3n Structural and functional studies of SF1B Pif1 from Thermus oshimai reveal dimerization-induced helicase inhibition.
Resolution2.533 Å
Binding residue
(original residue number in PDB)		P117 T118 G119 T129 H131 A138 V216 R302 R303 N356 N364 W396 H432 K433 R448 F451
Binding residue
(residue number reindexed from 1)		P51 T52 G53 T63 H65 A72 V150 R236 R237 N290 N298 W330 H366 K367 R382 F385
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003678 DNA helicase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0000723 telomere maintenance
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:6s3n, PDBe:6s3n, PDBj:6s3n
PDBsum6s3n
PubMed33784404
UniProtK7RJ88

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