Structure of PDB 6rt7 Chain B Binding Site BS01

Receptor Information
>6rt7 Chain B (length=160) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHIHWVLPAGMSAKMLGGVFKIDW
ICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFPPDES
IDLYQVIHKM
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6rt7 Flexible Binding of m6A Reader Protein YTHDC1 to Its Preferred RNA Motif.
Resolution1.73 Å
Binding residue
(original residue number in PDB)		K361 S362 N363 N367 W377 S378 R404 E405 W428 P431 M434 K472 I473 G474 R475 D476
Binding residue
(residue number reindexed from 1)		K18 S19 N20 N24 W34 S35 R61 E62 W81 P84 M87 K125 I126 G127 R128 D129
Binding affinityPDBbind-CN: Kd=3.7uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6rt7, PDBe:6rt7, PDBj:6rt7
PDBsum6rt7
PubMed31670957
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

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