Structure of PDB 6r5b Chain B Binding Site BS01

Receptor Information
>6r5b Chain B (length=191) Species: 1496 (Clostridioides difficile) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TIQQNKDTLSQIVVFPTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKI
KLLSGKLTDEKEYAYLKGVVPKGHEGTGKTWDDVPGLGGSTVALRIGFSN
KGKGHDAINLELHATAHAIDHIVLNDISKSAQFKQIFAKEGRSLGNVNFL
GVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNLAK
Ligand information
Receptor-Ligand Complex Structure
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PDB6r5b Molecular determinants of the mechanism and substrate specificity ofClostridium difficileproline-proline endopeptidase-1.
Resolution2.06 Å
Binding residue
(original residue number in PDB)		P100 K101 H103 W110 G115 L116 G117 G118 S119 H134 D135 L139 H142 H146 H150 N175 F178 E185 E189
Binding residue
(residue number reindexed from 1)		P71 K72 H74 W81 G86 L87 G88 G89 S90 H105 D106 L110 H113 H117 H121 N146 F149 E156 E160
Enzymatic activity
Enzyme Commision number 3.4.24.89: Pro-Pro endopeptidase.
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6r5b, PDBe:6r5b, PDBj:6r5b
PDBsum6r5b
PubMed31182482
UniProtQ183R7|PPEP1_CLOD6 Pro-Pro endopeptidase (Gene Name=zmp1)

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