Structure of PDB 6qic Chain B Binding Site BS01

Receptor Information
>6qic Chain B (length=626) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NMSIKEQRESLPVFQFRDQIIQAVKDNQILIVVGETGSGKTTQVTQYLAE
AGFTKYGMIGCTQPRRVAAVSVAKRVAEEVGCQLGQEVGYTIRFEDVTSP
ATKIKYMTDGMLQREILMDPDLKRYSVIMLDEAHERTIATDVLFALLKKT
VKRRPDLKVIVTSATLDAEKFSEYFNSCPIFTIPGRTFPVEILYSREPEP
DYLEAALTTVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKALGPSV
PELIILPIYSALPSEMQSRIFEPASRKVVIATNIAETAITIDYIYYVVDP
GFVKQNAYDPKLGMDSLVVTPISQAQANQRAGRAGRTGPGKCFRLYTEAA
YQSEMLPTTIPDIQRQNLANTILLLKAMGINDLLRFDFMDPPPVNTMLTA
LEELYALGALDDEGLLTRLGRKMADFPMEPSLSKVLIASVDKGCSDEMVT
IVSMLNLQQIFYRPKDKQQQADQKKAKFHDPTGDHLTLLNVYNAWKNSGY
SNAWCFENYIQARAMRRARDVRQQIVKIMERHRHPIISCGRDTDKIRQAL
CAGFFRNTARKDPGYKTLTEGTPVYLHPSSALFGKQAEWVLYHELVLTTK
EYMHFTTAIEPKWLVEAAPTFFKLAP
Ligand information
Receptor-Ligand Complex Structure
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PDB6qic Structural basis for RNA translocation by DEAH-box ATPases.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
R611 R612 R639 T654 G656 M657 R660 G774 Q775 E776 S806 T831 N832 I833 K853 L866 D974 P976 R1012 Q1073 I1077 R1080 H1128 P1129 F1134 T1149 K1151 Y1153 H1155
Binding residue
(residue number reindexed from 1)
R65 R66 R93 T108 G110 M111 R114 G228 Q229 E230 S260 T282 N283 I284 K304 L317 D425 P427 R463 Q524 I528 R531 H577 P578 F583 T598 K600 Y602 H604
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:6qic, PDBe:6qic, PDBj:6qic
PDBsum6qic
PubMed30828714
UniProtG0S700

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