Structure of PDB 6ppu Chain B Binding Site BS01

Receptor Information
>6ppu Chain B (length=752) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LGLFPPTDEQAAVIAAPPGPLVVIAGAGAGKTETMAARVVWLVANGFATP
SQVLGLTFTRKAAGQLLRRVRTRLARLATVSTYHAFAGTLLREHGLLLPV
EPDTRLLSETELWQLAYDVVCAHPGHLDTEKTPAAVTAMVLRLSGALAEH
LVDTDQLRDTHVELERLVHTLPAGPSQWLLRMLATQTERTELVPLIDALH
QRMRAEKVMDFGMQMAAAARLAARFPQVGEQLRQRFRVVLLDEYQDTGHA
QRIALSSLFGGGADDGLALTAVGDPIQSIYGWRGASLPRFTTDFPYGTPA
PTLELRTSWRNPPSTLHVANAVSEEARRVRALRPREPGTIRCALLNNVAA
ERDWVADHLARAYHGPTAAVLVRRNADAAPMAEALTARGVPVEVGLLAVP
EVADLVAMLRLIADPTAGSAVMRILTGPRWRFGARDIAALWRRAVELDLG
TADIVAQAAPDADTACVADAICDPGDAERYSPAGYERIVALGRELTMLRA
HLGHPLPELVAEVRRVLGLDAEARAARPVAAGWAGTENLDRFSDLVSDFA
GASVSALLAYLDAAVEVENGLAPAQILTVHAAKGLEWQVVAVPHLSARVF
PSTARTWLTDASDLPPLLRGDRAGVPVLDTSDIYDRKILSDKISDHKKSL
DQRRVDEERRLLYVAITRAEDTLLLSGHHWGATESKPRGPSEFLCELKTI
LEEGEIEHWPLRDQVVEALWPDHVHRGAQLVAAAMEGWAADVDALLAERE
RP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ppu Structures and single-molecule analysis of bacterial motor nuclease AdnAB illuminate the mechanism of DNA double-strand break resection.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		T80 R81 S219 Q220 F254 W325 R326 R436 N438 H665 R692 R746
Binding residue
(residue number reindexed from 1)		T59 R60 S176 Q177 F211 W282 R283 R373 N375 H580 R605 R654
Enzymatic activity
Enzyme Commision number 5.6.2.4: DNA 3'-5' helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016853 isomerase activity
GO:0043138 3'-5' DNA helicase activity
Biological Process
GO:0000725 recombinational repair
GO:0006281 DNA repair
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005829 cytosol
GO:0033202 DNA helicase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ppu, PDBe:6ppu, PDBj:6ppu
PDBsum6ppu
PubMed31740608
UniProtI7FZ56

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