Structure of PDB 6ppo Chain B Binding Site BS01

Receptor Information
>6ppo Chain B (length=235) Species: 463676 (Rhinovirus C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLPTRLPSGSQQFMTTEDEQSPNILPGFHPSKKIHIPGMITNVMHMARVD
SFIPINNIQGEVGKVSMYYITVTKKTVTERILVLPLEMSNTLFATTLLGE
VLNYYANWSGSITITFMCVCDAFSTGKFLVAYTPPGGKLPEDRKQAMLGV
HIIWDLGLQSSCTIVVPWISSGFYRRTKADSFTHGGYVSLWYQTAFVPPV
SGGTGSILATCSACPDMSVRMLRDSPMMEQKNELQ
Ligand information
>6ppo Chain D (length=25) Species: 463676 (Rhinovirus C) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
NINYYKDSASSGLSRDPSKFTQPLV
Receptor-Ligand Complex Structure
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PDB6ppo Cryo-EM structure of rhinovirus C15a bound to its cadherin-related protein 3 receptor.
Resolution3.2 Å
Binding residue
(original residue number in PDB)
D18 Q20 S21 P22 N23 G38 R48
Binding residue
(residue number reindexed from 1)
D18 Q20 S21 P22 N23 G38 R48
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:6ppo, PDBe:6ppo, PDBj:6ppo
PDBsum6ppo
PubMed32152109
UniProtE5D8F2|POLG_HRV15 Genome polyprotein

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