Structure of PDB 6pog Chain B Binding Site BS01

Receptor Information
>6pog Chain B (length=236) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DFCSERHNCMENSICRNLNDRAVCSCRDGFRALREDNAYCEDIDECAEGR
HYCRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENAL
CFNTVGGHNCVCKPGYTGNGTTCKAFCKDGCRNGGACIAANVCACPQGFT
GPSCETDIDECSDGFVQCDSRANCINLPGWYHCECRDGYHDNGMFSPSGE
SCEDIDECGTSCANDTICFNLDGGYDCRCCTGHHHH
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6pog Chain B Residue 905 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6pog NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance.
Resolution2.755 Å
Binding residue
(original residue number in PDB)		D440 I441 E443 N459 T460 G462 S463
Binding residue
(residue number reindexed from 1)		D42 I43 E45 N61 T62 G64 S65
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:6pog, PDBe:6pog, PDBj:6pog
PDBsum6pog
PubMed32198364
UniProtQ99435|NELL2_HUMAN Protein kinase C-binding protein NELL2 (Gene Name=NELL2)

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