Structure of PDB 6ph4 Chain B Binding Site BS01

Receptor Information
>6ph4 Chain B (length=460) Species: 224914 (Brucella melitensis bv. 1 str. 16M) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QATDPFRAAVEFTLMPMLITNPHLPDNPIVFANPAFLKLTGYEADEVMGR
NCRFLQGHGTDPAHVRAIKSAIAAEKPIDIDIINYKKSGEAFWNRLHISP
VHNANGRLQHFVSSQLDVTLELSRLVELEKERKTLSIETARSKDQLDYIV
EVANIGFWTREFYSGKMTCSAECRRIYGFTPDEPVHFDTILDLVVLEDRM
TVVQKAHQAVTGEPYSIEYRIVTRLGETRWLETRAKALTGENPLVLGIVQ
DVTERKKAEANKALVSREIAHRFKNSMAMVQSIANQTLRNTYDPEQANRL
FSERLRALSQAHDMLLKENWAGATIQQICATALAPFNSTFANRIHMSGPH
LLVSDRVTVALSLAFYELATNAVKYGALSNEKGVINITWAIMEDKGEKKF
HMRWAESRGPEVMQPARRGFGQRLLHSVLAEELKAKCDVEFAASGLLIDV
LAPITPEVFP
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6ph4 Chain B Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6ph4 Dimer Asymmetry and Light Activation Mechanism in Brucella Blue-Light Sensor Histidine Kinase.
Resolution3.25 Å
Binding residue
(original residue number in PDB)		E384 N388
Binding residue
(residue number reindexed from 1)		E367 N371
Annotation score4
Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Gene Ontology
Molecular Function
GO:0004673 protein histidine kinase activity
GO:0005524 ATP binding
GO:0009881 photoreceptor activity
GO:0016301 kinase activity
Biological Process
GO:0016310 phosphorylation
GO:0018106 peptidyl-histidine phosphorylation

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:6ph4, PDBe:6ph4, PDBj:6ph4
PDBsum6ph4
PubMed33879593
UniProtQ8YC53|LOVHK_BRUME Blue-light-activated histidine kinase (Gene Name=BMEII0679)

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