Structure of PDB 6pav Chain B Binding Site BS01

Receptor Information
>6pav Chain B (length=379) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDR
GVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRV
VSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIRE
ITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSN
MTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMS
QEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLK
AAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKF
GIGDGNLQYYLYNWKCPSMGAEKVGLVLQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6pav NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle.
Resolution2.52 Å
Binding residue
(original residue number in PDB)		V181 D183 D185 F188 R189 F190 T282 G284 Y296 H298 F311 S312 S405 G468 I469 G470 D471 G472 N473
Binding residue
(residue number reindexed from 1)		V65 D67 D69 F72 R73 F74 T166 G168 Y180 H182 F195 S196 S288 G351 I352 G353 D354 G355 N356
Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.97: glycylpeptide N-tetradecanoyltransferase.
Gene Ontology
Molecular Function
GO:0004379 glycylpeptide N-tetradecanoyltransferase activity
Biological Process
GO:0006499 N-terminal protein myristoylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6pav, PDBe:6pav, PDBj:6pav
PDBsum6pav
PubMed32103017
UniProtP30419|NMT1_HUMAN Glycylpeptide N-tetradecanoyltransferase 1 (Gene Name=NMT1)

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