Structure of PDB 6p59 Chain B Binding Site BS01

Receptor Information
>6p59 Chain B (length=196) Species: 11723 (Simian immunodeficiency virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EKMWIVRPVWRVDRRKIEQWHSLVKYHMYKGKKEAREWEYVPHFKVPWGW
WSHSEVHIPLGNNTKIKVTTYWNLTTEKGWLGTYGAALAYIDQKCDPPYF
TDIDPIVADSLIHKIYFPCFTDKAIRQAILGEKVLLCGFQRGHRDQVGTL
QYLAIQAWAREQVKKHGRKSARGPHQVTLPSRVHFPSLAYLCGTLA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6p59 Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6p59 Structural Basis for a Species-Specific Determinant of an SIV Vif Protein toward Hominid APOBEC3G Antagonism.
Resolution2.94221 Å
Binding residue
(original residue number in PDB)		H115 C121 C139 H145
Binding residue
(residue number reindexed from 1)		H113 C119 C137 H143
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0019058 viral life cycle
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0020002 host cell plasma membrane
GO:0030430 host cell cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6p59, PDBe:6p59, PDBj:6p59
PDBsum6p59
PubMed31830442
UniProtE1ANT9

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