Structure of PDB 6p3w Chain B Binding Site BS01

Receptor Information
>6p3w Chain B (length=257) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEY
KLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEV
AEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPA
NCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPES
LIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHGVSLLN
PPETLNL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6p3w Structural basis for the ORC1-Cyclin A association.
Resolution2.54 Å
Binding residue
(original residue number in PDB)		M210 I213 L214 W217 Q254 Y280 I281 T282 D283 T285
Binding residue
(residue number reindexed from 1)		M35 I38 L39 W42 Q79 Y105 I106 T107 D108 T110
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity
Biological Process
GO:0044772 mitotic cell cycle phase transition

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Molecular Function
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Biological Process
External links
PDB RCSB:6p3w, PDBe:6p3w, PDBj:6p3w
PDBsum6p3w
PubMed31309634
UniProtP20248|CCNA2_HUMAN Cyclin-A2 (Gene Name=CCNA2)

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