Structure of PDB 6org Chain B Binding Site BS01

Receptor Information

>6org Chain B (length=450) Species: 170187 (Streptococcus pneumoniae TIGR4) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQEDPERFNPS
QLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKE
ILSNPNYGNAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIF
STEGTSIRWIGNERGYAGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFS
IGEADVSIRPGWFYHEDQDPKSLEELVEIYFHSVGRGTPLLLNIPPNQAG
LFDAKDIERLYEFATYRNELYKEDLALGAEVSGPALSADFACRHLTDGLE
TSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIAAFHVQVEVDG
VWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKTPG

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

6org Chain B Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6org Two complementary alpha-fucosidases fromStreptococcus pneumoniaepromote complete degradation of host-derived carbohydrate antigens.
Resolution	1.72 Å
Binding residue (original residue number in PDB)	H346 D349 L351 S354 T443
Binding residue (residue number reindexed from 1)	H344 D347 L349 S352 T441
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0004560	alpha-L-fucosidase activity

	Biological Process
GO:0005975	carbohydrate metabolic process

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Molecular Function

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Biological Process

External links

PDB	RCSB:6org, PDBe:6org, PDBj:6org
PDBsum	6org
PubMed	31266803
UniProt	A0A0H2US78

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