Structure of PDB 6om2 Chain B Binding Site BS01
Receptor Information
>6om2 Chain B (length=310) Species:
9606
(Homo sapiens) [
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INTQVTPGNFMLKVHPVDLYYLVDVSASMHNNIEKLNSNDLSRKMAFFSR
DFRLGFGSYVDKTVSPYISIHPERIHNQCSDYNLDCMPPHGYIHVLSLTE
NITEFEKAVHRQKISGNIDTPEGGFDAMLQAAVCESHIGWRKEAKRLLLV
MTDQTSHLALDSKLAGIVCPNDGNCHLKNNVYVKSTTMEHPSLGQLSEKL
IDNNINVIFAVQGKQFHWYKDLLPLLPGTIAGEIESKAANLNNLVVEAYQ
KLISEVKVQVENQVQGIYFNITAICPDMEGCRNVSNDEVLFNVTVTMKNY
IIKPIGFNAK
Ligand information
>6om2 Chain E (length=10) Species:
9606
(Homo sapiens) [
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GRRGDLATIH
Receptor-Ligand Complex Structure
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PDB
6om2
General structural features that regulate integrin affinity revealed by atypical alpha V beta 8.
Resolution
2.77 Å
Binding residue
(original residue number in PDB)
S114 A115 S116 H118 Y172 N207 I208 T210 E212
Binding residue
(residue number reindexed from 1)
S26 A27 S28 H30 Y82 N117 I118 T120 E122
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6om2
,
PDBe:6om2
,
PDBj:6om2
PDBsum
6om2
PubMed
31792290
UniProt
P26012
|ITB8_HUMAN Integrin beta-8 (Gene Name=ITGB8)
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