Structure of PDB 6odf Chain B Binding Site BS01

Receptor Information
>6odf Chain B (length=419) Species: 11021 (Eastern equine encephalitis virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LDTHFTQYKLARPYIADCPNCGHSRCDSPIAIEEVRGDAHAGVIRIQTSA
MFGLKTDGVDLAYMSFMNGKTQKSIKIDNLHVRTSAPCSLVSHHGYYILA
QCPPGDTVTVGFHDGPNRHTCTVAHKVEFRPVGREKYRHPPEHGVELPCN
RYTHKRADQGHYVEMHQPGLVADHSLLSIHSAKVKITVPSGAQVKYYCKC
PDVREGITSSDHTTTCTDVKQCRAYLIDNKKWVYNSGRLPRGEGDTFKGK
LHVPFVPVKAKCIATLAPEPLVEHKHRTLILHLHPDHPTLLTTRSLGSDA
NPTRQWIERPTTVNFTVTGEGLEYTWGNHPPKRVWAQESGEGNPHGWPHE
VVVYYYNRYPLTTIIGLCTCVAIIMVSCVTSVWLLCRTRNLCITPYKLAP
NAQVPILLALLCCIKPTRA
Ligand information
Ligand IDU97
InChIInChI=1S/C6H10O10S/c7-1-2(8)4(16-17(12,13)14)6(11)15-3(1)5(9)10/h1-4,6-8,11H,(H,9,10)(H,12,13,14)/t1-,2+,3+,4-,6-/m0/s1
InChIKeyCOJBCAMFZDFGFK-BKBMJHBISA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7C1(C(C(OC(C1OS(=O)(=O)O)O)C(=O)O)O)O
CACTVS 3.385O[C@H]1O[C@H]([C@@H](O)[C@@H](O)[C@@H]1O[S](O)(=O)=O)C(O)=O
CACTVS 3.385O[CH]1O[CH]([CH](O)[CH](O)[CH]1O[S](O)(=O)=O)C(O)=O
OpenEye OEToolkits 2.0.7[C@H]1([C@@H]([C@@H](O[C@@H]([C@H]1OS(=O)(=O)O)O)C(=O)O)O)O
ACDLabs 12.01C1(C(C(=O)O)OC(O)C(C1O)OS(O)(=O)=O)O
FormulaC6 H10 O10 S
Name2-O-sulfo-beta-L-galactopyranuronic acid
ChEMBL
DrugBank
ZINC
PDB chain6odf Chain I Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6odf Cryo-EM structure of eastern equine encephalitis virus in complex with heparan sulfate analogues.
Resolution5.8 Å
Binding residue
(original residue number in PDB)		N80 H114
Binding residue
(residue number reindexed from 1)		N79 H113
Annotation score1
Enzymatic activity
Enzyme Commision number 3.4.21.90: togavirin.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Cellular Component
GO:0019028 viral capsid

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:6odf, PDBe:6odf, PDBj:6odf
PDBsum6odf
PubMed32245806
UniProtQ4QXJ7|POLS_EEEVF Structural polyprotein

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