Structure of PDB 6o8f Chain B Binding Site BS01

Receptor Information

>6o8f Chain B (length=591) Species: 1395 ([Bacillus] caldotenax)

VEGRFQLVAPYEPQGDQPQAIAKLVDGLRRGVKHQTLLGATGTGKTFTIS
NVIAQVNKPTLVIAHNKTLAGQLYSELKEFFPHNAVEYFVSYYDYYQPEA
YVPQTDTYIEKDAKINDEIDKLRHSATSALFERRDVIIVASVSSIYGLGS
PEEYRELVVSLRVGMEIERNALLRRLVDIQYDRNDIDFRRGTFRVRGDVV
EIFPASRDEHSIRVEFGDEIERIREVDALTGEVLGEREHVAIFPASHFVC
REEKMRLAIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMG
FSSGIENYSRHLALRPPGSTPYTLLDYFPDDFLIIVDESHVTLPQLRGMY
NGDRARKQVLVDHGFRLPSALDNRPLTFEEFEQKINQIIYVSATPGPYEL
EHSPGVVEQIIRPTGLLDPTIDVRPTKGQIDDLIGEIRERVERNERTLVT
TLTKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVG
INLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNANGHVIM
YADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTVKKEI

Ligand information

>6o8f Chain E (length=20)

gctctagattttcatacggc

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6o8f Mechanism of DNA Lesion Homing and Recognition by the Uvr Nucleotide Excision Repair System.
• Resolution: 2.81 Å
• Binding residue (original residue number in PDB): H65 N66 K67 S91 Y92 Y93 Y96 K111 A113 S141 S143 Y146 F249 S304 E307 Q346 M350 T454 K455 S477 R484 I502 N503 L504
• Binding residue (residue number reindexed from 1): H65 N66 K67 S91 Y92 Y93 Y96 K111 A113 S141 S143 Y146 F248 S303 E306 Q345 M349 T453 K454 S476 R483 I501 N502 L503

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0005524 ATP binding
• GO:0016787 hydrolase activity
• GO:0016887 ATP hydrolysis activity

Biological Process

• GO:0006289 nucleotide-excision repair

Cellular Component

• GO:0009380 excinuclease repair complex

External links

• PDB: RCSB:6o8f, PDBe:6o8f, PDBj:6o8f
• PDBsum: 6o8f
• PubMed: 31549070
• UniProt: P56981|UVRB_BACCA UvrABC system protein B (Gene Name=uvrB)