Structure of PDB 6o7g Chain B Binding Site BS01
Receptor Information
>6o7g Chain B (length=60) Species:
9606
(Homo sapiens) [
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SLVTCPICHAPYVEEDLLIQCRHCERWMHAGCESLFTEDDVEQAADEGFD
CVSCQPYVVK
Ligand information
>6o7g Chain A (length=8) Species:
9606
(Homo sapiens) [
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KGGAKRHR
Receptor-Ligand Complex Structure
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PDB
6o7g
Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.
Resolution
N/A
Binding residue
(original residue number in PDB)
L1504 E1516 L1519 L1520 I1521 Q1522 W1529 E1540
Binding residue
(residue number reindexed from 1)
L2 E14 L17 L18 I19 Q20 W27 E38
Enzymatic activity
Enzyme Commision number
2.1.1.364
: [histone H3]-lysine(4) N-methyltransferase.
External links
PDB
RCSB:6o7g
,
PDBe:6o7g
,
PDBj:6o7g
PDBsum
6o7g
PubMed
31127101
UniProt
O14686
|KMT2D_HUMAN Histone-lysine N-methyltransferase 2D (Gene Name=KMT2D)
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