Structure of PDB 6nod Chain B Binding Site BS01
Receptor Information
>6nod Chain B (length=344) Species:
6239
(Caenorhabditis elegans) [
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DDLLTRYRANPAMMKNLKLSDIRGALLKFAKDQVGSRFIQQELASSKDRF
EKDSIFDEVVSNADELVDDIFGNYVVQKFFEYGEERHWARLVDAIIDRVP
EYAFQMYACRVLQKALEKINEPLQIKILSQIRHVIHRCMKDQNGNHVVQK
AIEKVSPQYVQFIVDTLLESSNTIYEMSVDPYGCRVVQRCLEHCSPSQTK
PVIGQIHKRFDEIANNQYGNYVVQHVIEHGSEEDRMVIVTRVSNNLFEFA
THKYSSNVIEKCLEQGAVYHKSMIVGAACHHQEGSVPIVVQMMKDQYANY
VVQKMFDQVTSEQRRELILTVRPHIPVLRQFPHGKHILAKLEKY
Ligand information
>6nod Chain E (length=8) [
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uguauaua
........
Receptor-Ligand Complex Structure
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PDB
6nod
Engineering a conserved RNA regulatory protein repurposes its biological function in vivo .
Resolution
2.547 Å
Binding residue
(original residue number in PDB)
Q206 Q213 N246 Y247 Y280 R283 Q286 H319 R358 Q361 N393 Y394 K426 Y427 S429 N430 E433 Y470 N472 Y473 H506 H509
Binding residue
(residue number reindexed from 1)
Q33 Q40 N73 Y74 Y107 R110 Q113 H146 R185 Q188 N220 Y221 K253 Y254 S256 N257 E260 Y297 N299 Y300 H333 H336
Binding affinity
PDBbind-CN
: Kd=28.8nM
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
View graph for
Molecular Function
External links
PDB
RCSB:6nod
,
PDBe:6nod
,
PDBj:6nod
PDBsum
6nod
PubMed
30652968
UniProt
Q09487
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