Structure of PDB 6nod Chain B Binding Site BS01

Receptor Information
>6nod Chain B (length=344) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DDLLTRYRANPAMMKNLKLSDIRGALLKFAKDQVGSRFIQQELASSKDRF
EKDSIFDEVVSNADELVDDIFGNYVVQKFFEYGEERHWARLVDAIIDRVP
EYAFQMYACRVLQKALEKINEPLQIKILSQIRHVIHRCMKDQNGNHVVQK
AIEKVSPQYVQFIVDTLLESSNTIYEMSVDPYGCRVVQRCLEHCSPSQTK
PVIGQIHKRFDEIANNQYGNYVVQHVIEHGSEEDRMVIVTRVSNNLFEFA
THKYSSNVIEKCLEQGAVYHKSMIVGAACHHQEGSVPIVVQMMKDQYANY
VVQKMFDQVTSEQRRELILTVRPHIPVLRQFPHGKHILAKLEKY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6nod Engineering a conserved RNA regulatory protein repurposes its biological function in vivo .
Resolution2.547 Å
Binding residue
(original residue number in PDB)
Q206 Q213 N246 Y247 Y280 R283 Q286 H319 R358 Q361 N393 Y394 K426 Y427 S429 N430 E433 Y470 N472 Y473 H506 H509
Binding residue
(residue number reindexed from 1)
Q33 Q40 N73 Y74 Y107 R110 Q113 H146 R185 Q188 N220 Y221 K253 Y254 S256 N257 E260 Y297 N299 Y300 H333 H336
Binding affinityPDBbind-CN: Kd=28.8nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:6nod, PDBe:6nod, PDBj:6nod
PDBsum6nod
PubMed30652968
UniProtQ09487

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