Structure of PDB 6nm9 Chain B Binding Site BS01

Receptor Information
>6nm9 Chain B (length=1205) Species: 1410628 (Lachnospiraceae bacterium ND2006) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDYKGV
KKLLDRYYLSFINDVLHSIKLKNLNNYISLFRKKTRTEKENKELENLEIN
LRKEIAKAFKGNEGYKSLFKKDIIETILPEFLDDKDEIALVNSFNGFTTA
FTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNMDIFEKVDAIFDKH
EVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTESGE
KIKGLNEYINLYNQKTKQKLPKFKPLYKQVEGYTSDEEVLEVFRNTLNKN
SEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTISKDIFGEWNVIRDK
WNAEYDDIHLKKKAVVTEKYEDDRRKSFKKIGSFSLEQLQEYADADLSVV
EKLKEIIIQKVDEIYKVYGSSEKLFDADFVLEKSLKKNDAVVAIMKDLLD
SVKSFENYIKAFFGEKETNRDESFYGDFVLAYDILLKVDHIYDAIRNYVT
QKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSKYYLAIMDKKY
AKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKWMAYYNSEDIQ
KIYKNGTFKKGDMFNLNDCHKLIDFFKDSISRYPKWSNAYDFNFSETEKY
KDIAGFYREVEEQGYKVSFESASKKEVDKLVEEGKLYMFQIYNKDFSDKS
HGTPNLHTMYFKLLFDENNHGQIRLSGGAELFMRRASLKKEELVVHPANS
PIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAINKCPKNIFKIN
TEVRVLLKHDDNPYVIGIDRGERNLLYIVVVDGKGNIVEQYSLNEIINNF
NGIRIKTDYHSLLDKKEKERFEARQNWTSIENIKELKAGYISQVVHKICE
LVEKYDAVIALEDLNSGFKNSRVKVEKQVYQKFEKMLIDKLNYMVDKKSN
PCATGGALKGYQITNKFESFKSMSTQNGFIFYIPAWLTSKIDPSTGFVNL
LKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRTDADYIKKW
KLYSYGNRIRIFFDWEEVCLTSAYKELFNKYGINYQQDIRALLCEQSDKA
FYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYEAQEN
AILPKNADANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEWLEYA
QTSVK
Ligand information
>6nm9 Chain G (length=25) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aauuucuacuaaguguagauggaaa
....<<<<<.....>>>>>......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6nm9 Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins.
Resolution3.38 Å
Binding residue
(original residue number in PDB)
S14 K15 T16 R18 F19 K20 K51 G153 N157 K518 K520 N706 K707 S710 K712 S713 H714 G715 T716 H720 F745 I765 A766 N767 K768 N769 N772 K774 T777 L779 Y781 Y784 K785 R788 Q793 H797 N861 F863 Y872 L875 G902 S905 Q906 K953 K960
Binding residue
(residue number reindexed from 1)
S14 K15 T16 R18 F19 K20 K51 G153 N157 K506 K508 N693 K694 S697 K699 S700 H701 G702 T703 H707 F732 I752 A753 N754 K755 N756 N759 K761 T764 L766 Y768 Y771 K772 R775 Q780 H784 N848 F850 Y859 L862 G889 S892 Q893 K940 K947
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6nm9, PDBe:6nm9, PDBj:6nm9
PDBsum6nm9
PubMed31155345
UniProtA0A182DWE3

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